Annals of Clinical Nutrition and Metabolism

Volume 4 (1); December 2011

Original Articles

Factors Associated with Length of Hospital Stay in Pediatric Hematopoietic Stem Cell Transplantation Patients Administrating Parenteral Nutrition: Hyo Jung Park, Jung A Yoon, Do Young Kim, Yoon Jung Huh, Seon Young Chung, Yong Won In, Young Mee Lee, Jeong Meen Seo, Kie Ho Sohn; J Clin Nutr 2011;4(1):1-6. Published online December 1, 2011; DOI: https://doi.org/10.15747/jcn.2011.4.1.1

Abstract PDF: Purpose
Parenteral nutrition (PN) is a standard supportive care for pediatric patients undergoing hematopoietic stem cell transplantation (HSCT) in Samsung Medical Center. The objective of this study was to identify the factors associated with the length of hospital stay (LOS) in pediatric HSCT patients administrating PN routinely. Methods: This was a retrospective study for 128 pediatric HSCT patients from Aug. 2008 to Dec. 2009. Demographics, nutrition status on the first report in the nutrition support team, calories and nutrients supplied, PN duration, LOS, PN-induced complications, and laboratory data were collected from electronic medical records. Multivariate analyses were conducted to identify factors associated with LOS. Results: The median age of registered patients was 70 months (range 6∼239 months). Twenty-three patients (18.0%) were malnourished moderately to severely when PN was started. Number of autologous HSCT was larger than allogeneic HSCT (87 vs 41). In children undergoing HSCT, LOS was significantly correlated with PN duration (P＜0.001) and graft type (P＜0.001). Especially, in autologous peripheral blood stem cell transplantation (PBSCT), malnourished patients at the beginning of PN were shown the tendency to increase LOS (P=0.024) and PN duration (P=0.043). Conclusion: In pediatric HSCT patients administrating PN routinely, LOS was associated with a graft type of HSCT and PN duration. Especially for autologous PBSCT patients, the nutrition status at the beginning of PN had the influence on LOS and PN duration. During the peri-HSCT period, careful nutrition monitoring can prevent malnutrition, decrease PN duration, and shorten LOS. (JKSPEN 2011;4(1):1-6)

4 View
0 Download

Comparison of the Impact of Malnutrition by Nutritional Assessment and Screening Tools on Operative Morbidity after Gastric Cancer Surgery: Yoon Kim, Won Gyoung Kim, Hyuk Joon Lee, Mi Sun Park, Young Hee Lee, Seong Ho Kong, Han Kwang Yang; J Clin Nutr 2011;4(1):7-15. Published online December 1, 2011; DOI: https://doi.org/10.15747/jcn.2011.4.1.7

Abstract PDF: Purpose
This study aimed to evaluate the agreement of Seoul National University Hospital-Nutrition Screening Index (SNUH-NSI) and Nutrition Risk Screening-2002 (NRS- 2002) with patient generated-Subjective Global Assessment (PG-SGA) and the association between nutrition risk determined by these screening tools and operative morbidity after a gastrectomy for gastric cancer. Methods: This study enrolled 174 patients who had undergone a gastrectomy for gastric cancer at Seoul National University Hospital from March to July 2009. We assessed a nutrition risk by two nutrition screening tools (SNUH-NSI, NRS-2002) and a nutrition assessment tool (PG-SGA) at hospital admission. We collected general patient information, serum albumin level, cholesterol amount, total lymphocyte count, hemoglobin, and body mass index, operative method, hospital stay, and operative morbidity. Results: The mean age was 59.1±11.6 years, and 8.6% (n=15) of patients were assessed as having severe malnutrition by the PG-SGA. Agreement between the PG-SGA, SNUH-NSI (Պ=0.498, P＜0.001), and NRS-2002 (Պ= 0.439, P＜0.001) was moderate. Patients with a high risk of malnutrition by PG-SGA, SNUH-NSI, or those with advanced gastric cancer showed more operative morbidity (P＜0.05). There were no relationships between a high risk of malnutrition by NRS-2002 and operative morbidity. On multivariate analysis, malnutrition by PG-SGA (OR 2.159, 95% CI 0.693∼6.721) or SNUH-NSI (OR 2.630, 95% CI 0.906∼7.638) had a tendency to show higher operative morbidity, but it was not a significant independent risk factor. Conclusion: Both SNUH-NSI and NRS-2002 had moderate agreement with PG-SGA. Severe malnutrition risk as assessed by SNUH-NSI had an association with operative morbidity as PG-SGA did. SNUH-NSI was expected to be a valuable and efficient screening tool to detect malnutrition risk as much as PG-SGA. (JKSPEN 2011;4(1): 7-15)

5 View
0 Download

The Effect of Dietary Fiber on Metabolic Syndrome and Adiponectin: Ki Jong Lee, Ji Hyun Suh, Young Ahn, Sung Hae Ha, Ju Sang Park, Eun Jeong Jang, Sang Jong Park, Sang Jung Kim, Sang Woon Park, Hyun Wook Baik; J Clin Nutr 2011;4(1):16-20. Published online December 1, 2011; DOI: https://doi.org/10.15747/jcn.2011.4.1.16

Abstract PDF: Purpose
In Korea, the prevalence of metabolic syndrome has increased. The relationship between metabolic syndrome, adiponectin, and dietary components is widely known. However, the relation between cytokine and dietary components is not yet well studied in Korea. Methods: Five hundred and ninety-six Korean adults between 30 and 59 years of age were recruited by advertisement to the Bundang Jesaeng General Hospital (BJGH), and those not taking regular medications and without diagnoses of fulminant disease were included. Data was collected on anthropometric measurements, diagnostic parameters for metabolic syndrome (MetS), and 3-day dietary intakes from individuals in the study. Results: Serum adiponectin level was positively correlated with serum HDL-cholesterol level and was negatively correlated with BMI, waist circumference, and systolic and diastolic blood pressure. Intake of dietary fiber was high in the high-adiponectin group. Conclusion: High-fiber diet and adiponectin can be helpful for improving metabolic syndrome. (JKSPEN 2011; 4(1):16-20)

4 View
0 Download

The Effects of High Fat Formula on the Blood Glucose Control of Brain-injured Patients: A Pilot Study: Song Mi Lee, Sun Jeong Kim, Hye Kyung Chung, Joo Hye Jeon, Bo Dam Lee, B.A.1, Chang Ki Hong, Jong Sook Park, Chul Ho Chang; J Clin Nutr 2011;4(1):21-26. Published online December 1, 2011; DOI: https://doi.org/10.15747/jcn.2011.4.1.21

Abstract PDF: Purpose
Hyperlycemia after brain injury is known to be a risk factor that is correlated with hospital infection, mortality and the length of the hospital stay. There have been some reports about the use of a reduced-carbohydrate, modified high fat enteral formula for improving the blood glucose control and clinical outcomes of patients with type 2 diabetes. This pilot study evaluated the glucose control of brain-injured patients who were admitted into the neurointensive care unit (NCU) and they received either standard formula or high fat formula. Methods: Fourteen subjects were collected and they were divided into the experimental (high fat formula) and the control (standard formula) groups. We investigated the blood glucose levels, the total dose of insulin used, the number of patients who received insulin, the rate of hospital infection, the number of hospital days, the number of NCU days, the days of mechanical ventilation, the body mass index and the mental status of the subjects. Results: The hospital infection rate of the control group was higher than that of the experimental group, but the daily blood glucose level, the number of patients who received insulin and the total dose of insulin used were not statistically different between the two groups. The number of hospital days, the number of NCU days and the days on mechanical ventilation or the number of patients on mechanical ventilation were lower in the experimental group than that in the control group, but there were no statistically significant differences. Conclusion: These results suggest that the use of high fat enteral formula as compared to standard formula may decrease the hospital infection rate in critically ill patients after brain injury. But high fat formula did not have beneficial effects on the blood sugar level and insulin dosage. (JKSPEN 2011;4(1):21-26)

4 View
0 Download

First
Prev
Page of 1
Next
Last

Previous issues