Annals of Clinical Nutrition and Metabolism

Original Article

Relationship between Selenium Plasma Levels and Prognosis of Major Burn Patients: Seung Hyun Hwang, Tae Young Jang, Tae Young Jang, Hye Jung Han, Hye Jung Han, Go Woon Woo, Go Woon Woo; Surg Metab Nutr 2015;6(2):28-32. Published online December 30, 2015; DOI: https://doi.org/10.18858/smn.2015.6.2.28

Abstract PDF: Purpose:
Selenium is an important trace element for antioxidative function. Low selenium plasma level in sepsis is associated with high oxidative damage and increasing consumption of selenium, which is thought to affect severity of burns. This study was conducted to investigate a relationship between selenium plasma levels and prognosis of burn patients.
Materials and Methods:
In a retrospective review of 45 burn patients with more than 20% TBSA from January 2011 to May 2015, selenium plasma levels on days 2 to 7 after burn injury, abbreviated burn severity index (ABSI), mortality, length of stay in intensive care unit, and duration of intravenous antibiotics use were measured.
Results:
Selenium plasma levels on days 2 to 7 after burn injury were fairly correlated with ABSI (r=-0.640, P<0.001), TBSA (r=-0.640, P<0.001), duration of intravenous antibiotics use (r=-0.555, P<0.001), and length of stay in intensive care unit (r=-0.445, P=0.004). In comparison between survivor and non-survivor, statistical difference was observed between two selenium plasma levels (66.2±13.6 mcg/L versus 49.4±14.5 mcg/L, P=0.002).
Conclusion:
In this study, selenium plasma levels on days 2 to 7 after burn injury was related to prognosis of major burn patients.

Search