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A Case of Wernicke’s Encephalopathy during Long-term Total Parenteral Nutrition (TPN)
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Case Report A Case of Wernicke’s Encephalopathy during Long-term Total Parenteral Nutrition (TPN)
Su Jin Kim1, Yen Kyeung Han1, Bo Young Yeon1, Sung Mi Park1, Seung Yeon Im1, Moon Soo Lee, M.D., Ph.D.1,2, Gil Ho Kang, M.D., Ph.D.1,2

장기간 영양요법 중 발생한 Wernicke’s 뇌병증(Encephalopathy) 경험 1예
김수진1ㆍ한은경1ㆍ연보영1ㆍ박성미1ㆍ임승연1ㆍ이문수1,2ㆍ강길호1,2
Surgical Metabolism and Nutrition 2010;1(1):42-44.
Published online: December 30, 2010
1Nutritional Support Team, Soonchunhyang University Cheonan Hospital,
2Department of Surgery, College of Medicine, Soonchunhyang University, Cheonan, Korea

1순천향대학교 천안병원 영양지원팀,
2순천향대학교 의과대학 외과학교실
Received: 24 July 2010   • Revised: 14 December 1901   • Accepted: 30 July 2010
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Wernicke’s encephalopathy can develop from vitamin B1 (thiamine) deficiency and presents itself as ataxia, ophthalmoplegia, and mental confusion. One of its predisposing factors is long-term TPN. An adult patient with an entero-cutaneous fistula received total parenteral nutrition (TPN) for 2 months. After one month, the patient presented dizziness and ophthalmophlegia. The patient was diagnosed as thiamine deficient and subsequent thiamine administration brought dramatic recovery. To our knowledge, reports about Wernicke’s encephalopathy during long-term TPN are rare. (SMN 2010;1:42-44)


Ann Clin Nutr Metab : Surgical Metabolism and Nutrition
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