Annals of Clinical Nutrition and Metabolism

Assessment of Serum Retinol Binding Protein as a Marker of Nutritional Status after Pancreaticoduodenectomy: Sang In Bae, Hee Chul Yu, Mi Jin Jungc., Jae Do Yang, Dal Sik Kim, Min Ro Lee, Se Youl Lee, Baik Hwan Cho; Surg Metab Nutr 2013;4(2):25-30. Published online December 30, 2013

Abstract PDF: Purpose: Retinol binding protein (RBP) is a biochemical marker utilized for assessment of perioperative nutritional status and appropriateness of nutrition support. Due to short half-life and non-generalized measurement methods, it is not widely used, despite its sensitive response to protein and calories. The aim of this study was to investigate the usefulness of serum RBP concentrations in order to reflect the appropriateness of postoperative nutrition support in patients treated with pancreaticoduodenectomy.
Materials and Methods: We reviewed 36 patients treated with pancreaticoduodenectomy from December 2010 to May 2013. Serum concentrations of RBP, prealbumin, and transferrin were measured on the day before surgery and on postoperative day one, seven, and 14, retrospectively. Correlation of these parameters and other blood indexes used in nutritional evaluation, such as albumin and apolipoprotein A1 (apoA1), were analyzed.
Results: Twenty five patients were men and 11 were women. Mean age was 58.9±9.9 years. RBP concentrations showed a significant decrease on postoperative day one and showed a slight increase afterwards. RBP concentrations showed significant correlation with prealbumin preoperatively (r=0.73, P<0.0001) and showed correlation with apoA1 and prealbumin on postoperative day one (r=0.44, P=0.03 and r=0.66, P<0.0001, respectively). RBP concentrations on postoperative day seven showed correlation with prealbumin (r=0.78, P<0.0001) and on postoperative day 14, RBP showed significant correlation with apoA1 and prealbumin (r=0.54, P=0.02 and r=0.77, P<0.0001, respectively).
Conclusion: Postoperative serum concentrations of RBP have been shown to be a rapid, sensitive blood index, which is useful in surveillance of nutritional status. An abundant accumulation of data and attempts to utilize this marker by several hospitals are needed in order to generalize its use domestically. (SMN 2013;4:25-30)

4 View
0 Download

Multicenter, Prospective Randomized Controlled Trial Evaluating Postoperative Oral Nutritional Supplementation for Patients Who Underwent Major Gastrointestinal Surgery: Seong-Ho Kong, Seung Wan Ryu, Jun Seok Park, Ji Won Park, Kyung Won Seo, In Kyu Lee, Mi Ran Jeong, Dae Wook Hwang, Hoon Hur, Hyuk-Joon Lee, Guideline and Clinical Trial Committee of the Korean Society of Surgical Metabolism and Nutrition; Surg Metab Nutr 2013;4(2):31-36. Published online December 30, 2013

Abstract PDF: Patients undergoing major gastrointestinal surgery are potentially at high risk of malnutrition, and oral nutritional supplement solutions have been commercialized as an easily edible balanced nutritional source. A multicenter prospective randomized study to examine the efficacy of postoperative oral nutritional supplementation is ongoing in Korea. A total of 174 patients in eight institutes who are supposed to undergo major gastrointestinal organ resection or significant bowel reconstruction will be prescreened before the operation, and randomized to either the oral nutrition supplementation group or the control group when they are discharged after the operation. After discharge, patients in the oral nutrition supplementation group take 200 ml of Encover^? solution twice per day for eight weeks, thereafter the weight loss rate of each group compared with preoperative body weight will be compared with that of the control group as a primary endpoint. The secondary endpoints include weight loss rate compared with that at the time of discharge, changes of body mass index, biochemical serum parameters, patient-generated subjective global assessment, and anthropometric measurements (ClincalTrials.gov ID: NCT01838109). (SMN 2013;4:31-36)

4 View
0 Download

외과 대사 및 영양의 특징: 정미란ㆍ박영규ㆍ공성호ㆍ박준석ㆍ박지원ㆍ서경원ㆍ이인규ㆍ황대욱ㆍ허 훈ㆍ이혁준ㆍ대한외과대사영양학회 가이드라인/임상시험위원회; Surg Metab Nutr 2013;4(2):37-41. Published online December 30, 2013

PDF

4 View
0 Download

외과 환자 영양 선별 검사 및 영양 평가: 허 훈ㆍ서경원ㆍ공성호ㆍ박준석ㆍ박지원ㆍ이인규ㆍ황대욱ㆍ이혁준ㆍ대한외과대사영양학회 가이드라인/임상시험위원회; Surg Metab Nutr 2013;4(2):42-50. Published online December 30, 2013

PDF

4 View
0 Download

영양지원의 실제(1) - 영양 필요량 산출 및 영양공급경로의 결정: 공성호ㆍ박준석ㆍ박지원ㆍ서경원ㆍ이인규ㆍ정미란ㆍ황대욱ㆍ허 훈ㆍ이혁준ㆍ대한외과대사영양학회 가이드라인/임상시험위원회; Surg Metab Nutr 2013;4(2):51-57. Published online December 30, 2013

PDF

4 View
0 Download

Previous issues