Annals of Clinical Nutrition and Metabolism

Original Article

Relationship of Sarcopenia with the Outcomes of Patients who Underwent Surgery for Bile Duct Cancer: Hye Jin Kim, Min-Su Park, Bum-Soo Kim, Sang-Mok Lee; Surg Metab Nutr 2019;10(2):54-58. Published online December 30, 2019; DOI: https://doi.org/10.18858/smn.2019.10.2.54

Abstract PDF: Purpose:
This study investigated the impact of Sarcopenia by examining the psoas muscle on the outcomes after bile duct resection for bile duct cancer.
Materials and Methods:
This study retrospectively analyzed 101 patients who underwent surgery for bile duct cancer between January 2006 and December 2015 at Kyung-Hee University Hospital. Skeletal muscle mass was evaluated by performing preoperative computed tomography to define Sarcopenia. Patients were classified into two groups by the median value of the psoas muscle index (PMI).
Results:
The median value of the psoas muscle index in female patients was 463.9 mm²/m², and the median value of the psoas muscle index in males was 688.7 mm²/m². In the sarcopenia group, the 1, 3, and 5-year recurrence free survival rates were 74.5%, 52.9%, and 27.5%, respectively. On the other hand, in the non-sarcopenia group the 1, 3, and 5-year recurrence free survival rates were 50%, 34%, and 28%, respectively. In the sarcopenia group, the 1, 3, and 5-year overall survival rates were 84.3%, 54.9%, and 31.4%, respectively. In the non-sarcopenia group, 1, 3, and 5-year overall survival rates were 58%, 40%, and 32%, respectively. However, recurrence-free survival and overall survival were not correlated with sarcopenia (P=0.131, P=0.163).
Conclusion:
Sarcopenia using the psoas muscle index (PMI) has no impact on outcomes of bile duct cancer patients who underwent surgery. (Surg Metab Nutr 2019;10:-58)

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