Purpose: Pancreaticoduodenectomy (PD) is associated with high rates of postoperative morbidity. The benefits of enteral nutritional support compared with parenteral nutrition are widely accepted. However, fear of postoperative ileus and anastomotic leakage has been the barrier for early feeding after abdominal surgery. The aim of this study was to prospectively assess the safety, tolerability, and outcome of early enteral feeding after PD.
Materials and Methods: All patients who underwent PD between October 2008 and March 2009 were prospectively divided into one of the following two study groups: early enteral nutrition (EN) and traditional nutrition (TN). Fourteen patients received EN, and 13 patients received TN. Fully informed consent was obtained from all the patients.
Results: Twenty-seven patients were enrolled in this study. EN was discontinued in two patients due to abdominal bloating and abdominal pain. Age, gender, preoperative weight loss, and medical comorbidity were similar between the two groups. The overall postoperative morbidity was 33.3% (EN group) and 30.7% (TN group), and the differences in the values were not statistically significant. The results of blood tests obtained on postoperative days 7 and 14 showed no statistically significant difference between the two groups. On postoperative day 7, patients in the EN group showed a weight gain, but patients in the TN group showed continuing weight loss.
Conclusion: Early enteral feeding following PD is a feasible procedure associated with improvements in early postoperative nutritional status. (SMN 2011;2:16-20)