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Development of the Korean Version of the Gastrointestinal Quality of Life Index Questionnaire
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In Jun Yang, Heung-Kwon Oh, Jeehye Lee, Jung Wook Suh, Hong-min Ahn, Hyeonjeong Park, Hyun Hee Sim, Yong Beom Cho, In Kyu Lee, Seungbum Ryoo, Dong-Won Lee, Duck-Woo Kim, Sung-Bum Kang
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Ann Clin Nutr Metab 2022;14(1):32-37. Published online June 1, 2022
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DOI: https://doi.org/10.15747/ACNM.2022.14.1.32
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 Abstract
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- Purpose: To establish a standardized quality of life measurement that allows global cross-study comparisons, we translated the Gastrointestinal Quality of Life Index (GIQLI) into Korean and linguistically validated the Korean version of the GIQLI (K-GIQLI) in patients who underwent colorectal surgery.
Materials and Methods: A cross-cultural adaptation of the original GIQLI was created based on the established guidelines. Based on participation in a cognitive interview, 20 patients with colorectal cancer were enrolled in the study. To ensure that the Korean version of the questionnaire was understood as intended, the time needed to complete the questionnaire was measured, and three additional items related to comprehension were added.
Results: From May to July 2021, two translators, whose native language was Korean translated the GIQLI items into Korean, and a native English editor who had no knowledge of the original questionnaire translated the items back into English. In the cognitive interview, the median age of the patients was 61.8 (range: 44~82) years, and the median time required to complete the questionnaire was 6.5 (range: 5~10) min. For the language and cultural adaptation process, the participants’ comprehension of the questionnaire was measured on a scale of 1~5, with a mean score of 4 (range: 3~4).
Conclusion: The K-GIQLI was developed and did not exhibit a significant difference from the original English version in terms of social, linguistic, and cultural differences between the Western world and Republic of Korea.
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Efficacy of Intravenous Ferric Carboxymaltose in Patients with Acute Post-Operative Anemia after Colorectal Cancer Surgery
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Young Ju Oh, Dae Hee Pyo, Jung Kyong Shin, Yoon Ah Park, Jung Wook Huh, Hee Cheol Kim, Seong Hyeon Yun, Woo Yong Lee, Yong Beom Cho
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Surg Metab Nutr 2020;11(2):61-65. Published online December 30, 2020
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DOI: https://doi.org/10.18858/smn.2020.11.2.61
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Abstract
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- Purpose: This study evaluated the efficacy of administering intravenous ferric carboxymaltose (Ferinject®) in patients with acute post-operative anemia after colorectal surgery.
Materials and Methods: Patients with colorectal cancer, who underwent colectomy from January 2017 to July 2019 at the Samsung Medical Center, were retrospectively reviewed. Depending on their body weight, patients were administered 500 mg or 1000 mg of ferric carboxymaltose (ferric carboxymaltose group, 92 patients). The primary outcome evaluated was serum hemoglobin level on post-operative day 21. The secondary outcome was the number of hemoglobin responders, defined as the proportion of patients with normalized serum hemoglobin on post-operative day 21 (hemoglobin level of 12 g/dL or more for male, 11 g/dL or more for female), and a serum hemoglobin increase of 2 g/dL or more from baseline (day 0).
Results: Of the 560 patients who underwent colectomy, 92 patients (median age, 67 years; women 59.8%; mean baseline hemoglobin level 10.7 g/dL) received intravenous ferric carboxymaltose. Compared with the no-ferric carboxymaltose group, patients in the ferric carboxymaltose group experienced significantly greater improvement in serum hemoglobin level (post-operative day 5: 8.9 g/dL, P=0.09; post-operative day 21: 11.7 g/dL, P=0.006). The increase in hemoglobin levels was significantly greater in the ferric carboxymaltose group (2.7 g/dL) than the no-ferric carboxymaltose group (2.1 g/dL) (P=0.002).
Conclusion: Findings of this study indicate a better outcome after administering intravenous ferric carboxymaltose, which results in continuous increase in the levels of hemoglobin during the early post-operative period after colorectal cancer surgery.
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