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Review Article
- Drug-Induced Vitamin Deficiency
- Jung Won Jung, So Young Park, Hyunah Kim
- Ann Clin Nutr Metab 2022;14(1):20-31. Published online June 1, 2022
- DOI: https://doi.org/10.15747/ACNM.2022.14.1.20
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Abstract
PDF
ePub - Drug-induced vitamin depletion can occur in hospitalized patients due to the administration of specific medications, which could potentially adversely affect patient outcomes. Signs and symptoms related to vitamin deficiency while taking certain medications should be monitored carefully and managed appropriately if those deficiencies are clinically significant. This article reviews potential drug-induced vitamin depletion and discusses the evidence supporting vitamin deficiency related to the use of specific medications.
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Citations
Citations to this article as recorded by
- Recent Advances on the Role of B Vitamins in Cancer Prevention and Progression
Zachary Frost, Sandra Bakhit, Chelsea N. Amaefuna, Ryan V. Powers, Kota V. Ramana
International Journal of Molecular Sciences.2025; 26(5): 1967. CrossRef - A review of current trends of vitamin identification and quantification by chromatography from food samples
Ionut Avrămia, Mircea-Adrian Oroian, Radu-Cristian Oiţă
Journal of Food Composition and Analysis.2024; 131: 106244. CrossRef - SARS-CoV-2 Infection: What Is Currently Known about Homocysteine Involvement?
Nina Filip, Elena Cojocaru, Oana Viola Badulescu, Andreea Clim, Alin Constantin Pinzariu, Gabriela Bordeianu, Alina Elena Jehac, Cristina Elena Iancu, Cristiana Filip, Minela Aida Maranduca, Ivona Andreea Sova, Ionela Lacramioara Serban
Diagnostics.2022; 13(1): 10. CrossRef
- Recent Advances on the Role of B Vitamins in Cancer Prevention and Progression
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Original Article
- Analysis of Adverse Reactions Associated with Parenteral Nutrition Use in Korea
- Sera Lee, Miyoung Ock, Seonghee Kim, Hyunah Kim
- J Clin Nutr 2017;9(1):16-20. Published online June 30, 2017
- DOI: https://doi.org/10.15747/jcn.2017.9.1.16
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Abstract
PDFePub
Purpose:
To evaluate the clinical manifestations of adverse drug reactions (ADRs) of parenteral nutrition (PN) use in Korea.
Methods:
The Korean Adverse Event Reporting System (KAERS) database records in 2015 on PN-treated patients were used. ADRs classified as “certain,” “probable,” and “possible” based on the WHO-Uppsala Monitoring Centre criteria were analyzed.
Results:
In total, 21,436 ADRs from 2,346 patients were included for analysis. The mean patient age was 57.1 years and the mean number of ADRs per patient was 9.1. ADRs were reported frequently with amino acids solutions (682 events, 40.8%), followed by combinations products (519 events, 31.1%), and fat emulsions (363 events, 21.7%). The frequent ADRs were gastrointestinal (507 events, 30.3%), skin (343 events, 20.5%), general disorders (239 events, 14.3%), and central/peripheral nervous system disorders (165 events, 9.9%). The common clinical symptoms were nausea (321 events, 19.2%), vomiting (105 events, 6.3%), and vein pain (102 events, 6.1%). Serious ADRs accounted for 220 patients (9.4%) and dyspnea was the most frequent clinical manifestation.
Conclusion:
This study analyzed the KAERS data in 2015 from patients treated with PN and revealed gastrointestinal and skin disorders to be the leading ADRs.
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