Annals of Clinical Nutrition and Metabolism

Volume 15 (1); April 2023

Editorial

Working together for nutrition care in hospitals: Jee-Eun Chung; Ann Clin Nutr Metab 2023;15(1):1-1. Published online April 1, 2023; DOI: https://doi.org/10.15747/ACNM.2023.15.1.1

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Reviews

Efficacy of monounsaturated fatty acids in reducing risk of the cardiovascular diseases, cancer, inflammation, and insulin resistance: a narrative review: Ki Hyun Kim, Yoonhong Kim, Kyung Won Seo; Ann Clin Nutr Metab 2023;15(1):2-7. Published online April 1, 2023; DOI: https://doi.org/10.15747/ACNM.2023.15.1.2

Abstract PDF

Purpose: The purpose of this review is to explore the potential benefits of monounsaturated fatty acids (MUFAs), specifically those found in olive oil, on weight loss, cardiovascular disease, cancer, inflammation, and insulin resistance. Additionally, this review examines the use of olive oil–based intravenous lipid emulsions (ILEs) in providing parenteral nutrition to patients with diverse needs.
Current concept: MUFAs, found in olive oil, nuts, and some animal foods, have been found to have numerous health benefits. A diet high in MUFAs can aid in weight loss and reduce the risk of cardiovascular disease. Olive oil, in particular, has been linked to a lower risk of cancer, inflammation, and insulin resistance. In addition, olive oil–based ILEs have been utilized for over two decades and are well tolerated by patients requiring parenteral nutrition.
Conclusion: A diet rich in MUFAs, specifically from olive oil, can provide numerous health benefits, including weight loss and reducing the risk of cardiovascular disease, cancer, inflammation, and insulin resistance. Additionally, olive oil–based ILEs have been shown to effectively provide nutrients to diverse populations requiring parenteral nutrition and have demonstrated the ability to preserve immune function and induce less lipid peroxidation than other ILEs. Further research is needed to fully understand the potential benefits of MUFAs and olive oil-based ILEs, but current evidence suggests that they may be a valuable addition to a healthy diet and medical treatment.

Citations

Citations to this article as recorded by

Effects of daily extra virgin olive oil consumption on biomarkers of inflammation and oxidative stress: a systematic review and meta-analysis
Jéssica Vidal Damasceno, Anderson Garcez, Andressa Anelo Alves, Isabella Rosa da Mata, Simone Morelo Dal Bosco, Juliano Garavaglia
Critical Reviews in Food Science and Nutrition.2026; 66(2): 392. CrossRef
Applying Wild Mistol Fruits (Sarcomphalus Mistol) from the Paraguayan Chaco as Value-Added Food Ingredients
Villalba R., Belotto J., Coronel E., Carvajal M., Recalde C., Caballero S., Friesen A., Mereles L.
Plant Foods for Human Nutrition.2026;[Epub] CrossRef
Multi-Omics Integration Reveals Key Genes, Metabolites and Pathways Underlying Meat Quality and Intramuscular Fat Deposition Differences Between Tibetan Pigs and Duroc × Tibetan Crossbred Pigs
Junda Wu, Qiuyan Huang, Baohong Li, Zixiao Qu, Xinming Li, Fei Li, Haiyun Xin, Jie Wu, Chuanhuo Hu, Sen Lin, Xiangxing Zhu, Dongsheng Tang, Chuang Meng, Zongliang Du, Erwei Zuo, Fanming Meng, Sutian Wang
Animals.2026; 16(2): 214. CrossRef
The MetaboHealth Score Enhances Insulin Resistance Metabotyping for Targeted Fat Loss: The PERSON Study
Jordi Morwani‐Mangnani, Fatih A. Bogaards, Alexander Umanets, Gabby B. Hul, Anouk Gijbels, Gijs H. Goossens, Joris Deelen, Marian Beekman, Lydia Afman, Ellen E. Blaak, P. Eline Slagboom
Obesity.2026; 34(3): 550. CrossRef
Video and Text‐Based Supplemental Health Information and Consumer Willingness to Pay for Nutrient‐Enhanced Eggs
Edeoba W. Edobor, Michael J. Best, Anita R. Best, Ondulla T. Toomer
Agribusiness.2026;[Epub] CrossRef
Optimizing Pistacia lentiscus (mastic tree) food and healthcare applications: phytochemical composition, extraction methods, quality control, and novel delivery systems
Mohamed A. Anwar, Yuting Fu, Haroun Khan, Mohamed A. Farag
Phytochemistry Reviews.2026;[Epub] CrossRef
The impact of Lactiplantibacillus plantarum on the cream composition: Insight into changes of vitamin D3 content and fatty acid composition
Tetiana Dyrda-Terniuk, Viorica Railean, Aleksandra Bogumiła Florkiewicz, Justyna Walczak-Skierska, Mateusz Kolankowski, Joanna Rudnicka, Dorota Białczak, Paweł Pomastowski
International Dairy Journal.2025; 161: 106118. CrossRef
Palmitoleic and oleic fatty acids as biomarkers for coronary heart disease: A predictive model
Guangzhou Wang, Lin Zhou, Zhengfang Wang, Asmaa Ali, Liang Wu
Irish Journal of Medical Science (1971 -).2025; 194(1): 59. CrossRef
Macrophages: their role in immunity and their relationship with fatty acids in health and disease
Mayte Rueda-Munguía, Luis Alberto Luévano-Martínez, Gerardo García-Rivas, Elena Cristina Castillo, Omar Lozano
Frontiers in Immunology.2025;[Epub] CrossRef
Evaluation of the Nutritional Value of Prunus dulcis Blossoms and the Antioxidant Compounds of Their Extracted Oil Using Green Extraction Method
Theodoros Chatzimitakos, Vassilis Athanasiadis, Konstantina Kotsou, Ioannis Makrygiannis, Eleni Bozinou, Stavros I. Lalas
Applied Sciences.2024; 14(5): 2001. CrossRef
Oleic Acid and Succinic Acid: A Potent Nutritional Supplement in Improving Hepatic Glycaemic Control in Type 2 Diabetic Sprague–Dawley Rats
Kemmoy G. Lattibeaudiere, Ruby Lisa Alexander-Lindo, Mozaniel Oliveira
Advances in Pharmacological and Pharmaceutical Sciences.2024;[Epub] CrossRef

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Selenium deficiency and supplementation in infants: a narrative review: Ji Young Lee, Min Jung Kang, Hyun Jeong Kim, Sung Yun Suh, Yoon Sook Cho, Sook Hee An; Ann Clin Nutr Metab 2023;15(1):8-14. Published online April 1, 2023; DOI: https://doi.org/10.15747/ACNM.2023.15.1.8

Abstract PDF

Purpose: This review aims to provide an overview of the factors and clinical outcomes associated with selenium deficiency and the guidelines on the optimal selenium supplementation in infants.
Current concept: Selenium is a cofactor required to maintain the activity of glutathione peroxidase and is an essential trace element in the human body. Selenium is involved in many stages of oxidative injury within the human body. In severe cases, selenium deficiency may lead to cardiomyopathy. Particularly in infants, the risk factors for selenium deficiency are preterm birth and long-term parenteral nutrition. Several studies have been conducted on the relationship between selenium deficiency and bronchopulmonary dysplasia, retinopathy of prematurity, and sepsis, all of which are common diseases in preterm infants. In the past, 2–3 mcg/kg/day of intravenous selenium supplementation was recommended in preterm infants with selenium deficiency. However, recent studies have suggested that only 2–3 mcg/kg/day can prevent further decreases of selenium level in the blood of preterm infants, and that higher supplementation of 1.5–4.5 mcg/kg/day or 7 mcg/kg/day is necessary to reach the level of healthy infants at term. The recommended dose of selenium through enteral nutrition for preterm infants is 1.3–4.5 mcg/kg/day or 5–10 mcg/kg/day, depending on the guideline.
Conclusion: Adequate selenium administration is required for adequate nutritional support in infants to prevent selenium deficiency, and more studies should be conducted to establish dosing guidelines considering risk factors in preterm infants.

Citations

Citations to this article as recorded by

Effect of Standard Care Pathway Implementation on Clinical Outcomes and Protocol Utilization in Infants With Gastroschisis
Alexandra Barone-Camp, Ana Ibarra Meraz, Samantha Bothwell, Sage A. Vincent, Theresa Grover, Stephanie Bourque, Kimberly Vollrath, Jose Diaz-Miron, Shannon Acker
Journal of Pediatric Surgery.2025; 60(11): 162499. CrossRef

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Original Articles

Preoperative consumption of a carbohydrate drink before laparoscopic cholecystectomy is safe and beneficial in Korea: a non-randomized controlled study: Yoo Jin Choi, Yoonhyeong Byun, Seong Mi Yang, Ho-Jin Lee, Hongbeom Kim; Ann Clin Nutr Metab 2023;15(1):15-21. Published online April 1, 2023; DOI: https://doi.org/10.15747/ACNM.2023.15.1.15

Abstract PDF Supplementary Material

Purpose: Overnight fasting prior to elective surgery is the traditional way of avoiding the risk of aspiration during anesthesia induction. However, it causes mental and metabolic stress to patients. Therefore, we investigated the safety and potential benefits of the preoperative consumption of a carbohydrate drink.
Methods: This was a single-center prospective, nonrandomized study with questionnaire. Patients scheduled for elective laparoscopic cholecystectomy were included. There was no restriction on age, underlying diseases, and biliary drainage prior to surgery. They were preoperatively given either a carbohydrate drink or were instructed to fast from midnight before surgery. Perioperative emotional status was measured using the visual analog scale.
Results: The 132 patients completed the questionnaire, with 68 receiving the carbohydrate drink and 64 following nil per oral after-midnight instruction. There were no postoperative complications related to preoperative drink consumption or the cholecystectomy procedure itself in both groups. There were no significant differences in all the assessed feelings postoperatively except that preoperative discomforts, such as hunger and thirst, were significantly more alleviated in the group of preoperative consumption of a carbohydrate drink.
Conclusion: Preoperative consumption of a carbohydrate drink was found to be safe and effective in alleviating preoperative discomfort in elective surgery patients, including older patients and those with underlying comorbidities, who were at greater risk for aspiration. Therefore, we recommend considering preoperative drink consumption as an alternative to traditional overnight fasting in elective surgery patients.

Citations

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MODERN CONCEPT OF POSTOPERATIVE ANALGESIA IN PATIENTS UNDERGOING URGENT LAPAROSCOPIC CHOLECYSTECTOMY
O. PYLYPENKO, O. KRAVETS
Pain anesthesia and intensive care.2024; (4(109)): 55. CrossRef

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Comparison of a volume-based feeding protocol with standard feeding for trauma patients in intensive care units in Korea: a retrospective cohort study: Juhong Park, Yesung Oh, Songhee Kwon, Ji-hyun Lee, Mihyang Kim, Kyungjin Hwang, Donghwan Choi, Junsik Kwon; Ann Clin Nutr Metab 2023;15(1):22-29. Published online April 1, 2023; DOI: https://doi.org/10.15747/ACNM.2023.15.1.22

Abstract PDF

Purpose: Although early enteral nutrition for critically ill patients is essential, it is difficult to provide enteral nutrition to trauma patients in early hospitalization stages due to frequent surgeries and examinations. We aimed to identify the effect of achieving early enteral nutrition goals and improving outcomes through a volume-based feeding (VBF) protocol for trauma patients.
Methods: Patients who were admitted to the trauma intensive care units (TICUs) of the Ajou University Hospital from January 2020 to September 2021 and received enteral tube feeding for at least 7 days were studied. An institution-specific VBF protocol was developed, and nurses were trained in its execution. We retrospectively compared outcomes, such as in-hospital mortality and initial nutritional goal achievement, between the new and standard protocols.
Results: Among 2,935 patients, 109 met the inclusion criteria. Of these, 64 patients received nutrition through VBF, with no feeding intolerance symptoms. The VBF group started enteral nutrition approximately 16.9 hours earlier and group achieved 80% of the target calorie and protein intake approximately one day faster than the control group (n=45). The average calorie supply per body weight per day was 4.9 kcal/kg/day more in the VBF group. An increase of 0.2 g/kg/day was also observed in protein uptake. However, mortality and adverse hospital events did not differ between the groups.
Conclusion: The VBF protocol for patients admitted to the TICU increased the initial nutrient supply without risk of feeding intolerance, but there was no improvement in major clinical outcomes, including mortality and adverse hospital events.

Citations

Citations to this article as recorded by

Early initiation of gastric tube feeding: ultrasound assessment. A prospective interventional study
Islam M. Elbardan, Ahmed A. Alla Ossman, Nada El Kayal, Assem A. ElRazek Abd-Rabih
Research and Opinion in Anesthesia & Intensive Care.2024; 11(4): 270. CrossRef

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Effects of nutritional status and support on the survival of COVID-19 patients in a single tertiary-center intensive care unit in Korea: a case-control study: Na Gyeong Lee, Hye Jin Kim, Ji Gyeong Kang, Do Hyeon Jeon, Mi Seung Kwak, So Hyun Nam; Ann Clin Nutr Metab 2023;15(1):30-37. Published online April 1, 2023; DOI: https://doi.org/10.15747/ACNM.2023.15.1.30

Abstract PDF

Purpose: It is important to understand the nutritional status of critically ill COVID-19 patients and to provide adequate associated support. We attempted to determine how nutritional status and the amount of nutritional support provided to critically ill patients affect their survival.
Methods: We retrospectively reviewed the medical records of patients admitted to the intensive care unit of Dong-A University Hospital between January and December 2021. We divided the patients into survivors and those who died during COVID-19 treatment and compared and analyzed their clinical parameters, nutrition-related indicators, nutritional status, and nutritional support.
Results: Of 70 patients reviewed, 57 survived. Mortality was higher in the older group (P=0.006). The patients who underwent ventilator, extracorporeal membrane oxygenation, or continuous renal replacement therapy showed higher mortality. Nutritional status at the time of admission and the nutritional requirements did not differ among patient groups. However, the actual amounts of calories (P<0.001) and protein (P=0.019) supplied were lower in the mortality group. Serum C-reactive protein level was higher (P=0.002) and serum albumin level was lower in those who did not survive (P<0.001) compared with surviving patients at discharge.
Conclusion: We did not determine whether the initial nutritional status of patients with COVID-19 affected their survival due to various factors associated with the severity of the disease. However, given the similarities between disease severity and nutritional status at the time of admission, our results indicate that adequate nutritional support can contribute to survival in critically ill COVID-19 patients with pneumonia.

Citations

Citations to this article as recorded by

Current practices and challenges in nutrition support team activities, 2025 in Korea: a multicenter cross-sectional descriptive study
So Hyun Nam
Ann Clin Nutr Metab.2025; 17(2): 97. CrossRef
The association between enteral nutrition with survival of critical patients with COVID‐19
Maryam Gholamalizadeh, Zahra Salimi, Khadijeh Abbasi Mobarakeh, Zahra Mahmoudi, Shirin Tajadod, Mahdi Mousavi Mele, Farkhondeh Alami, Bojlul Bahar, Saeid Doaei, Sara Khoshdooz, Masoume Rahvar, Somayeh Gholami, Masoume Pourtaleb
Immunity, Inflammation and Disease.2024;[Epub] CrossRef

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